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Imiquimod
Price range: 59 CAD through 261 CAD
Products Details
Product Description
– Imiquimod (R 837) is an immune response modifier that acts as a toll-like receptor 7 agonist.
Web ID
– T0134
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C14H16N4
Citations
– 1. Wang Y, Gong N, Ma C, et al. An amphiphilic dendrimer as a light-activable immunological adjuvant for in situ cancer vaccination. Nature Communications. 2021, 12(1): 1-16.
2. Chen X, Chen Y, Ou Y, et al. Bortezomib inhibits NLRP3 inflammasome activation and NF-κB pathway to reduce psoriatic inflammation. Biochemical Pharmacology. 2022, 206: 115326.
3. Chen Y, Chen X, Liang S, et al. Chlorquinaldol inhibits the activation of nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing protein 3 inflammasome and ameliorates imiquimod-induced psoriasis-like dermatitis in mice. Chemico-Biological Interactions. 2022, 365: 110122.
4. Zhou Y, Yang Z, Ou Y, et al.Discovery of a selective NLRP3-targeting compound with therapeutic activity in MSU-induced peritonitis and DSS-induced acute intestinal inflammation.Cellular and Molecular Life Sciences.2023, 80(8): 230.
5. Zeng Y, Luo M, Yao Z, et al.Adiponectin inhibits ROS/NLRP3 inflammatory pathway through FOXO3A to ameliorate oral submucosal fibrosis.Odontology.2024: 1-15.
References
– Gibson SJ, et al. Cell Immunol. 2002 Jul-Aug;218(1-2):74-86.
CAS Number
– 99011-02-6
Molecular Weight
– C14H16N4
Compound Purity
– 0.9966
SMILES
– C(C(C)C)N1C=2C=3C(N=C(N)C2N=C1)=CC=CC3
Target
– Autophagy|||Carbonic Anhydrase
Pathway
– Autophagy|||Immunology/Inflammation|||Microbiology/Virology
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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