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Products Details
Product Description
– IDO1 and HDAC1 Inhibitor (Compound 10) is a dual IDO1 and HDAC1 inhibitor with IC50s of 69.0 nM and 66.5 nM, respectively[1].
Web ID
– HY-112147
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H22BrFN8O4
References
– [1]Fang K, et al. Discovery of Novel Indoleamine 2,3-Dioxygenase 1 (IDO1) and Histone Deacetylase (HDAC) Dual Inhibitors. ACS Med Chem Lett. 2018 Mar 26;9(4):312-317.
CAS Number
– 2227044-16-6
Molecular Weight
– 597.40
SMILES
– BrC1=CC(N/C(C2=NON=C2NCCNC(C3=CC=C(C(NC4=C(N)C=CC=C4)=O)C=C3)=O)=N/O)=CC=C1F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HDAC;Indoleamine 2,3-Dioxygenase (IDO)
Isoform
– HDAC1;IDO1
Pathway
– Cell Cycle/DNA Damage;Epigenetics;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
