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HSK0935
$133 – $1,480
Products Details
Product Description
– HSK0935 is a potent, highly selective and orally available SGLT2 inhibitor with an IC50 of 1.3 nM. Antihyperglycemic activities[1].
Web ID
– HY-101782
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C22H25ClO7
References
– [1]Li Y, et al. Discovery of a Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor (HSK0935) for the Treatment of Type 2 Diabetes. J Med Chem. 2017 May 25;60(10):4173-4184.
CAS Number
– 1638851-44-1
Molecular Weight
– 436.88
Compound Purity
– 96.63
SMILES
– ClC(C=C1)=C(CC2=CC=C(OCC)C=C2)C=C1[C@@]3(OC4)[C@H](O)[C@@H](O)[C@H](O)[C@@]4(OC)O3
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– SGLT
Isoform
– SGLT2
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
