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Products Details
Product Description
– HNMPA is a membrane impermeable insulin receptor tyrosine kinase inhibitor. HNMPA inhibits serine and tyrosine autophosphorylation by the human insulin receptor. HNMPA has no effect on protein kinase C or cyclic AMP-dependent protein kinase activities[1][2]
Web ID
– HY-101962
Shipping
– Room temperature
Molecular Formula
– C11H11O4P
References
– [1]K Baltensperger, et al. Catalysis of serine and tyrosine autophosphorylation by the human insulin receptor. Proc Natl Acad Sci U S A. 1992 Sep 1;89(17):7885-9.|[2]Peter Kovacs, et al. In vivo electrophysiological effects of insulin in the rat brain. Neuropeptides. 2009 Aug;43(4):283-93.
CAS Number
– 132541-52-7
Molecular Weight
– 238.18
SMILES
– OC(P(O)(O)=O)C1=CC=C2C=CC=CC2=C1
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Insulin Receptor
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
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