Download Files:
Products Details
Product Description
– HJC0152 (free base) is an orally active and potent inhibitor of STAT3. HJC0152 (free base) inhibits cell cycle progression and induces apoptosis. HJC0152 (free base) significantly suppresses MDA-MB-231 xenograft tumor growth in mice[1].
Web ID
– HY-W369099
Shipping
– Room temperature
Molecular Formula
– C15H13Cl2N3O4
References
– [1]Chen H, et al. Discovery of O-Alkylamino Tethered Niclosamide Derivatives as Potent and Orally Bioavailable Anticancer Agents. ACS Med Chem Lett. 2013 Feb 14;4(2):180-185.
CAS Number
– 1420290-88-5
Molecular Weight
– 370.19
SMILES
– NCCOC1=C(C=C(Cl)C=C1)C(=O)NC2=C(Cl)C=C([N+](=O)[O-])C=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis, STAT
Pathway
– Apoptosis, JAK/STAT Signaling, Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
