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Products Details
Product Description
– HIV-1 protease-IN-5 (Compound 13c) is a HIV-1 protease inhibitor with an IC50 of 1.64 nM. HIV-1 protease-IN-5 shows remarkable activity against wild-type and DRV-resistant HIV-1 variants[1].
Web ID
– HY-147650
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C27H29F3N2O7S
References
– [1]Zhu M, et al. Design and biological evaluation of novel HIV-1 protease inhibitors with isopropanol as P1′ ligand to enhance binding with S1′ subsite. Bioorg Med Chem. 2020 Aug 15;28(16):115623.
CAS Number
– 2525173-96-8
Molecular Weight
– 582.59
SMILES
– C[C@H](CN(S(=O)(C1=CC=C(C=C1)C(F)(F)F)=O)C[C@H]([C@@H](NC(C2=CC(O)=C(C=C2)O)=O)CC3=CC=CC=C3)O)O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HIV Protease
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
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