Download Files:
Products Details
Product Description
– HIV-1 invistor-50 is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that targets HIV-1 reverse transcriptase (RT) (IC50=50 nM). HIV-1 inhibitor-50 shows significant antiviral activity, with EC50s of 2.22-53.3nM against HIV-1 IIIB and its mutant strains[1].
Web ID
– HY-152160
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C24H18FN5O2
References
– [1]Sun Y, et al. Lead Optimization and Avoidance of Metabolic-perturbing Motif Developing Novel Diarylpyrimidines as Potent HIV-1 NNRTIs. J Med Chem. 2022 Dec 8;65(23):15608-15626.
CAS Number
– 2834087-69-1
Molecular Weight
– 427.43
SMILES
– CC1=C(OC2=C3COCC3=NC(NC4=CC(F)=C(C=C4)C#N)=N2)C(C)=CC(/C=C/C#N)=C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HIV;Reverse Transcriptase
Isoform
– HIV-1
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
