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Products Details
Product Description
– hCAII-IN-4 (Compound 12j) is a potent hCA II inhibitor with an IC50 of 7.78 μM. hCAII-IN-4 also inhibits β-glucuronidase with an IC50 of 773.9 μM[1].
Web ID
– HY-150973
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C31H23NO9
References
– [1]Arif N, et al. Synthesis, Biological Evaluation, and In Silico Studies of Novel Coumarin-Based 4 H, 5 H-pyrano [3, 2-c] chromenes as Potent β-Glucuronidase and Carbonic Anhydrase Inhibitors. ACS Omega, 2022.
CAS Number
– 2816080-18-7
Molecular Weight
– 553.52
SMILES
– O=C(C(C1C2=CC=CC=C2OCC(C3=O)=CC4=C(O3)C=CC=C4)=C(N)OC(C5=C(O6)C=C(O)C=C5)=C1C6=O)OCC
Clinical Information
– No Development Reported
Research Area
– Cancer; Metabolic Disease; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase
Isoform
– CA Ⅱ
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
