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H-(Gly)3-Lys(N3)-OH
SKU
HY-151782-Get quote
Category Reference compound
Tags ADC Linker, Antibody-drug Conjugate/ADC Related, Others
Products Details
Product Description
– The azide function is widely used for coupling to alkyne-containing fragments via the renowned Click reaction. Polyglycine fragments containing up to 7 glycines are reported to bind to surfaces and have potential application in nanotechnology constructs: constructs of Gly7-NHCH2-fragment containing peptides bind on mica surface in aqueous solution[1][2].
Web ID
– HY-151782
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C12H21N7O5
References
– [1]Le Chevalier Isaad A, et al. Side chain-to-side chain cyclization by click reaction. J Pept Sci. 2009 Jul;15(7):451-4.|[2]Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789.
CAS Number
– 2250437-45-5
Molecular Weight
– 343.34
SMILES
– NCC(NCC(NCC(N[C@H](C(O)=O)CCCCN=[N+]=[N-])=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.