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GSK3004774
$280 – $5,900
Products Details
Product Description
– GSK3004774 is a potent, nonabsorbable agonist of CaSR, with an pEC50 of 7.3, 6.6 and 6.5 for human, mouse and rat CaSR, respectively. GSK3004774 shows an EC50 of 50 nM for human CaSR[1].
Web ID
– HY-107773
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C32H40N4O3
References
– [1]Sparks SM, et al. Identification of potent, nonabsorbable agonists of the calcium-sensing receptor for GI-specific administration. Bioorg Med Chem Lett. 2017 Oct 15;27(20):4673-4677.
CAS Number
– 2138814-32-9
Molecular Weight
– 528.69
Compound Purity
– 98.11
SMILES
– O=C(NCCCN1CCC(C(O)=O)CC1)C(C=C2)=CC=C2N(CC3)C[C@H]3N[C@H](C)C4=CC=CC5=C4C=CC=C5
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– CaSR
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
