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GNF-5837
Price range: 69 CAD through 1,107 CAD
Products Details
Product Description
– GNF-5837 is a specific, and orally bioavailable pan-TRK inhibitor for TrkA/TrkB (IC50: 8/12 nM).
Web ID
– T6097
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C28H21F4N5O2
Citations
– 1. Qin Q, Fu Q, Wang X, et al.Design, synthesis and biological evaluation of novel indolin-2-one derivatives as potent second-generation TRKs inhibitors.European Journal of Medicinal Chemistry.2023: 115291.
References
– Albaugh P, et al. ACS Med Chem Lett. 2012, 3(2), 140-145.
CAS Number
– 1033769-28-6
Molecular Weight
– C28H21F4N5O2
Compound Purity
– 0.9929
SMILES
– Cc1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1Nc1ccc2C(=Cc3ccc[nH]3)C(=O)Nc2c1
Pathway
– Tyrosine Kinase/Adaptors|||Angiogenesis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
