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Products Details
Product Description
– GNF-1331 is a potent, selective, and orally bioavailable porcupine inhibitor (IC50 = 12 nM). Blocking abnormal Wnt signaling is an attractive treatment for a variety of cancers.
Web ID
– T31983
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H20N6O2S2
References
– Discovery of Pyridinyl Acetamide Derivatives as Potent, Selective, and Orally Bioavailable Porcupine Inhibitors Dai Cheng, Jun Liu, Dong Han, Guobao Zhang, Wenqi Gao, Mindy H. Hsieh, Nicholas Ng, Shailaja Kasibhatla, Celin Tompkins, Jie Li, Auzon Steffy, Fangxian Sun, Chun Li, H. Martin Seidel, Jennifer L. Harris, and Shifeng Pan Publication Date (Web): May 10, 2016 (Letter) doi: 10.1021/acsmedchemlett.6b00038
CAS Number
– 603101-22-0
Molecular Weight
– C20H20N6O2S2
SMILES
– C(CC)N1C(=NN=C1SCC(NC=2SC=3C(N2)=CC=C(OC)C3)=O)C=4C=CN=CC4
Target
– Others
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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