GNE-9815

SKU T9585-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 93 CAD through 2,464 CAD

Products Details

Product Description

– GNE-9815 (3-(2-cyanopropan-2-yl)-N-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide) is a high kinase-selective inhibitor of RAF and targets KRAS-mutant cancers through combination therapy.

Web ID

– T9585

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H22FN5O2

References

– Huestis MP, et al. Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a Pyridopyridazinone pan-RAF Kinase Inhibitor. ACS Med Chem Lett. 2021 Apr 21;12(5):791-797.

CAS Number

– 2729996-45-4

Molecular Weight

– C26H22FN5O2

Compound Purity

– 0.9873

SMILES

– Cc1cc(F)c(NC(=O)c2cccc(c2)C(C)(C)C#N)cc1-c1cnc2c(cnn(C)c2=O)c1

Pathway

– MAPK|||GPCR/G Protein

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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