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GNE-616
Price range: 4,352 CAD through 7,840 CAD
Products Details
Product Description
– GNE-616 is a highly potent, metabolically stable, orally bioavailable, and subtype-selective Nav1.7 inhibitor [Ki: 0.79 nM, Kd: 0.38 nM for hNav1.7] for the treatment of chronic pain.
Web ID
– T11439
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H23F4N5O3S
References
– McKerrall SJ, et al. Structure- and Ligand-Based Discovery of Chromane Arylsulfonamide Nav1.7 Inhibitors for the Treatment of Chronic Pain. J Med Chem. 2019 Apr 25;62(8):4091-4109.
CAS Number
– 2349371-81-7
Molecular Weight
– C24H23F4N5O3S
SMILES
– C(F)(F)(F)[C@@H]1C[C@@H](N(CC1)[C@@H]2C=3C(=CC(S(NC=4C=CN=CN4)(=O)=O)=C(F)C3)OCC2)C5=CC=CC=N5
Target
– Others
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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