GNE-375

SKU T27423-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 190 CAD through 2,512 CAD

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Product Description

– GNE-375 is a selective and potent BRD9 inhibitor (IC50: 5 nM).GNE-375 inhibits BRD4, TAF1, and CECR2, and can be used to study epigenetic resistance.

Web ID

– T27423

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H29N3O5

References

– Terry D Crawford, et al. Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3534-3541.

CAS Number

– 1926989-06-1

Molecular Weight

– C25H29N3O5

Compound Purity

– 0.9932

SMILES

– COc1cc(c(OC)cc1C(=O)N1CCOCC1)-c1cn(CC=CC)c(=O)c2[nH]c(C)cc12

Pathway

– Chromatin/Epigenetic|||Proteases/Proteasome|||Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

GNE-375

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