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GN44028
Price range: 102 CAD through 1,397 CAD
Products Details
Product Description
– GN44028 (N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine) is a hypoxia-inducible factor inhibitor of (HIF)-1 (IC50: 14 nM). GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity. However, It can not be suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization.
Web ID
– T15396
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C18H15N3O2
References
– Minegishi H, et al. Discovery of Indenopyrazoles as a New Class of Hypoxia Inducible Factor (HIF)-1 Inhibitors. ACS Med Chem Lett. 2013 Jan 27;4(2):297-301.
CAS Number
– 1421448-26-1
Molecular Weight
– C18H15N3O2
Compound Purity
– 0.982
SMILES
– C1c2ccccc2-c2[nH]nc(Nc3ccc4OCCOc4c3)c12
Target
– Others
Pathway
– Chromatin/Epigenetic|||Angiogenesis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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