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GMQ
SKU
HY-107757-10 mg
Category Reference compound
Tags Membrane Transporter/Ion Channel, Neurological Disease, Sodium Channel
$32 – $170
Products Details
Product Description
– GMQ is a ASIC (acid-sensing ion) channel activator with an EC50 value of 1.83 mM for ASIC3 at pH 7.4. GMQ opens only ASIC3 but no other ASICs at pH 7.4. GMQ can be used for neurological disease research[1].
Web ID
– HY-107757
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Molecular Formula
– C10H12ClN5
References
– [1]Alijevic O, Kellenberger S. Subtype-specific modulation of acid-sensing ion channel (ASIC) function by 2-guanidine-4-methylquinazoline. J Biol Chem. 2012 Oct 19;287(43):36059-70.
CAS Number
– 5361-15-9
Molecular Weight
– 237.69
Compound Purity
– 99.69
SMILES
– CC1=NC(NC(N)=N)=NC2=CC=CC=C12.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– H2O : 3.33 mg/mL (ultrasonic)
Target
– Sodium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.