Gartisertib
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Gartisertib

SKU T10407-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 218 CAD through 3,776 CAD

Products Details

Product Description

– Gartisertib (VX-803) is an orally active and selective Rad3-related protein (ATR) inhibitor with antitumor activity, inhibiting the antiproliferative effect induced in ccRCC cells, and inhibiting ATR-driven phosphorylation of checkpoint kinase 1 (Chk1), useful for studying solid tumors.

Web ID

– T10407

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H29F2N9O3

References

– Frank T. Zenke, et al. Abstract 369: Antitumor activity of M4344, a potent and selective ATR inhibitor, in monotherapy and combination therapy. Experimental and Molecular Therapeutics.

CAS Number

– 1613191-99-3

Molecular Weight

– C25H29F2N9O3

Compound Purity

– 0.9952

SMILES

– O=C(NC=1C=NC=C(F)C1N2CCC(C(=O)N3CCN(CC3)C4COC4)CC2)C=5C(=NN6C=C(F)C=NC56)N

Target

– Others

Pathway

– DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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