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Products Details
Product Description
– Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1), this suppression leads to the inhibition of dendritic cell-specific transmembrane protein (DC-STAMP) expression and reduces osteoclast fusion.
Web ID
– TN1663
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C30H44O4
References
– Ganoderic acid DM, a natural triterpenoid, induces DNA damage, G1 cell cycle arrest and apoptosis in human breast cancer cells.Fitoterapia. 2012 Mar;83(2):408-14.
CAS Number
– 173075-45-1
Molecular Weight
– C30H44O4
SMILES
– [H][C@@]1(CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CCC(=O)C(C)(C)[C@]1([H])CC3=O)[C@H](C)CCC=C(/C)C(O)=O
Pathway
– Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Endocrinology/Hormones
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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