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G0507
$600 – $3,000
Products Details
Product Description
– G0507, a pyrrolopyrimidinedione compound, is a potent LolCDE ABC Transporter inhibitor. G0507 is a inhibitor of Escherichia coli growth and induces the extracytoplasmic σE stress response. G0507 acts as a chemical probe to dissect lipoprotein trafficking in Gram-negative bacteria[1].
Web ID
– HY-124658
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C18H15N3O3S
References
– [1]Nickerson NN, et al. A Novel Inhibitor of the LolCDE ABC Transporter Essential for Lipoprotein Trafficking in Gram-Negative Bacteria. Antimicrob Agents Chemother. 2018 Mar 27;62(4).
CAS Number
– 1223998-29-5
Molecular Weight
– 353.40
Compound Purity
– 98.33
SMILES
– O=C1NC(NC(C2=CC=C(C)S2)=C3C4=CC=C(OC)C=C4)=C3C(N1)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : 5 mg/mL (ultrasonic)|H2O : 0.1 mg/mL (ultrasonic)
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
