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Fuscin
3,600 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– Fuscin is a quinonoid fungal metabolite originally isolated from O. fuscum that has diverse biological activities. It inhibits binding of the ADP/ATP translocase inhibitor atractyloside to rat liver mitochondria in an ADP-dependent manner when used at a concentration of 50 μM in a radioligand binding assay. Fuscin (20 μM) reduces the glutathione content of rat liver mitochondria to 28% of controls and inhibits NADH oxidation in sonicated pigeon heart mitochondria preparations in a concentration-dependent manner. It competes with macrophage inflammatory protein 1α (MIP-1α) for binding to CCR5 chemokine receptors in vitro with an IC50 value of 21 μM.
Web ID
– T37714
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H16O5
CAS Number
– 83-85-2
Molecular Weight
– C15H16O5
SMILES
– CC1OC(=O)C=C2C3=C(OC(C)(C)CC3)C(=O)C(O)=C12 |t:5,7,19|
Pathway
– Others
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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