FM26
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FM26

SKU T11308-25 mg Category Brand:

Price range: 3,152 CAD through 5,440 CAD

Products Details

Product Description

– FM26 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells. FM26 is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists with an IC50 of 264 nM.

Web ID

– T11308

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H15ClF3N3O3

References

– Meijer FA, et al.Ligand-Based Design of Allosteric Retinoic Acid Receptor-Related Orphan Receptor γt (RORγt) Inverse Agonists.J Med Chem. 2020 Jan 9;63(1):241-259.

CAS Number

– 2407981-35-3

Molecular Weight

– C22H15ClF3N3O3

SMILES

– C(NC1=CC=C(C(O)=O)C=C1)C=2C(=NOC2C=3C=CNC3)C4=C(C(F)(F)F)C=CC=C4Cl

Target

– Dehydrogenase

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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