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Fluralaner
Price range: 46 CAD through 94 CAD
Products Details
Product Description
– Fluralaner (A1443) is an isoxazoline ectoparasiticide. It potently and selectively inhibits binding of the GABA receptor channel blocker EBOB to housefly head membranes (IC50: 455 pM).
Web ID
– T5330
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H17Cl2F6N3O3
Citations
– 1. Gastaldi M S, Felsztyna I, Miguel V, et al.Theoretical and Experimental Study of Molecular Interactions of Fluralaner with Lipid Membranes.Journal of Agricultural and Food Chemistry.2023
2. Li B J, Wang K K, Yu Y, et al.PxRdl2 dsRNA increased the insecticidal activities of GABAR-targeting compounds against Plutella xylostella.Pesticide Biochemistry and Physiology.2023: 105548.
3. Rodriguez M A, Felsztyna I, GarcÃa D A, et al.Interaction of fluralaner with binary model membranes. Potential implications in the selectivity for invertebrates/vertebrates.Journal of Molecular Liquids.2024: 124891.
References
– Ozoe Y, et al. The antiparasitic isoxazoline A1443 is a potent blocker of insect ligand-gated chloride channels. Biochem Biophys Res Commun. 2010 Jan 1;391(1):744-9.
CAS Number
– 864731-61-3
Molecular Weight
– C22H17Cl2F6N3O3
Compound Purity
– 0.9977
SMILES
– Cc1cc(ccc1C(=O)NCC(=O)NCC(F)(F)F)C1=NOC(C1)(c1cc(Cl)cc(Cl)c1)C(F)(F)F
Pathway
– Neuroscience|||Membrane transporter/Ion channel|||Microbiology/Virology
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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