Fluorobexarotene

SKU T11303-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 293 CAD through 6,224 CAD

Products Details

Product Description

– Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene. Fluorobexarotene  is a potent retinoid-X-receptor (RXR) agonist, with a Ki value of 12 nM and an EC50 value of 43 nM for RXRα receptor. Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene.

Web ID

– T11303

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H27FO2

References

– Wagner CE, et al. Modeling, synthesis and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene). J Med Chem. 2009 Oct 8;52(19):5950-66.

CAS Number

– 1190848-23-7

Molecular Weight

– C24H27FO2

Compound Purity

– 0.9923

SMILES

– CC1=CC2=C(C=C1C(=C)C1=CC(F)=C(C=C1)C(O)=O)C(C)(C)CCC2(C)C

Target

– Others

Pathway

– Metabolism

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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