Flumequine

$55$61

Products Details

Product Description

– Flumequine (R-802) is a quinolone antibiotic, and acts as a topoisomerase II inhibitor, with an IC50 of 15 μM (3.92 μg/mL).

Web ID

– HY-B0526

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C14H12FNO3

References

– [1]Kashida Y, et al. Mechanistic study on flumequine hepatocarcinogenicity focusing on DNA damage in mice. Toxicol Sci. 2002 Oct;69(2):317-21.|[2]Aller-Morán LM, et al. Evaluation of the in vitro activity of flumequine against field isolates of Brachyspira hyodysenteriae. Res Vet Sci. 2015 Dec;103:51-3.|[3]Giraud E, et al. Mechanisms of quinolone resistance and clonal relationship among Aeromonas salmonicida strains isolated from reared fish with furunculosis. J Med Microbiol. 2004 Sep;53(Pt 9):895-901.

CAS Number

– 42835-25-6

Molecular Weight

– 261.25

Compound Purity

– 99.89

SMILES

– O=C(C1=CN2C(C)CCC3=C2C(C1=O)=CC(F)=C3)O

Clinical Information

– No Development Reported

Research Area

– Infection; Cancer

Solubility

– DMSO : 7.69 mg/mL (ultrasonic)

Target

– Antibiotic;Bacterial;Topoisomerase

Isoform

– Quinolone;Topo II

Pathway

– Anti-infection;Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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