FD1024
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FD1024

SKU T79456-5 mg Category Brand:

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Product Description

– FD1024 is a potent PIM inhibitor, displaying inhibitory concentrations (IC50s) of 1.96 nM, 38.9 nM, and 4.17 nM for PIM1, PIM2, and PIM3, respectively. It demonstrates significant antiproliferative effects on several AML cell lines, with IC50 values of 0.16 μM for EOL-1, 0.12 μM for MV-4-11, 1.05 μM for KG-1, and 1.39 μM for MOLM-16. Additionally, FD1024 has shown antitumor efficacy in murine models [1].

Web ID

– T79456

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H20F2N4O2S

CAS Number

– 1422456-47-0

Molecular Weight

– C21H20F2N4O2S

SMILES

– FC1=C(C(F)=CC=C1)C2=NC(C(NC=3C(O[C@H]4CC[C@H](N)CC4)=CC=NC3)=O)=CS2

Pathway

– Chromatin/Epigenetic|||JAK/STAT signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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