Download Files:
Products Details
Product Description
– Enalapril (MK-421) is an angiotensin-converting enzyme (ACE) inhibitor, can be used for hypertensive diseases research[1][2].
Web ID
– HY-B0331
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C20H28N2O5
Citations
– Am J Transl Res. 2022 Jan 15;14(1):211-222.|Int J Clin Exp Pathol. 2020 May 1;13(5):827-836.|Nat Commun. 2023 May 2;14(1):2523.|Ren Fail. 2023 Sep 19;45(2):2253924.|Environ Pollut. 2019 Apr;247:927-934.|Toxicol Lett. 2019 Jul;309:42-50.|Toxicology. 2023 Jan 24;153442.
References
– [1]Serge Sicouri, et al. Antiarrhythmic effects of losartan and enalapril in canine pulmonary vein sleeve preparations. J Cardiovasc Electrophysiol. 2011 Jun;22(6):698-705.|[2]Rokhsareh Meamar, et al. Enalapril protects endothelial cells against induced apoptosis in Alzheimer’s disease. J Res Med Sci. 2013 Mar;18(Suppl 1):S1-5.|[3]Talita A Cunha, et al. Effect of stearic acid on enalapril stability and dissolution from multiparticulate solid dosage forms. AAPS PharmSciTech. 2013 Sep;14(3):1150-7.|[4]A Ravati, et al. Enalapril and moexipril protect from free radical-induced neuronal damage in vitro and reduce ischemic brain injury in mice and rats. Eur J Pharmacol. 1999 May 28;373(1):21-33.
CAS Number
– 75847-73-3
Molecular Weight
– 376.45
SMILES
– O=C(O)[C@H]1N(C([C@H](C)N[C@H](C(OCC)=O)CCC2=CC=CC=C2)=O)CCC1
Clinical Information
– Launched
Research Area
– Cardiovascular Disease; Cancer
Solubility
– 10 mM in DMSO
Target
– Angiotensin-converting Enzyme (ACE)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
