EHT 1610
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EHT 1610

SKU T15204-1 mg Category Brand:

Price range: 141 CAD through 2,128 CAD

Products Details

Product Description

– EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively. EHT 1610 has an inhibitory effect on leukemia, regulating cell cycle and inducing cell apoptosis.

Web ID

– T15204

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H14FN5O2S

References

– Chaikuad A, et al. An Unusual Binding Model of the Methyl 9-Anilinothiazolo[5,4-f] quinazoline-2-carbimidates (EHT 1610 and EHT 5372) Confers High Selectivity for Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases. J Med Chem. 2016;59(22):10315-1032

CAS Number

– 1425945-60-3

Molecular Weight

– C18H14FN5O2S

Compound Purity

– 0.9859

SMILES

– COC(=N)c1nc2ccc3ncnc(Nc4ccc(OC)cc4F)c3c2s1

Target

– Others

Pathway

– Tyrosine Kinase/Adaptors|||Cell Cycle/Checkpoint|||Proteases/Proteasome|||NF-κB|||PI3K/Akt/mTOR signaling|||Stem Cells

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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