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Products Details
Product Description
– Eg5-IN-1 (compound 6c) is a potent kinesin family motor protein (Eg5) inhibitor with an IC50 value of 1.97 µM. Eg5-IN-1 can be used in research of cancer[1].
Web ID
– HY-155134
Shipping
– Room temperature
Molecular Formula
– C23H16ClFN4O
References
– [1]Ranade SD, et, al. Design, synthesis, molecular dynamics simulation, MM/GBSA studies and kinesin spindle protein inhibitory evaluation of some 4-aminoquinoline hybrids. Comput Biol Chem. 2023 Aug;105:107881.
Molecular Weight
– 418.85
SMILES
– ClC1=CC=C2C(N=CC=C2NC3=CC=C(C(N/N=C/C4=CC=C(F)C=C4)=O)C=C3)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Kinesin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
