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Products Details
Product Description
– E3 ligase Ligand 10 serves as a ligand for E3 ubiquitin ligase and can be conjugated to a protein ligand through a linker, resulting in the formation of PROTACs. These PROTACs act as inducers of ubiquitination-mediated degradation, specifically targeting cancer-promoting proteins[1].
Web ID
– T17868
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C47H52N4O7
References
– Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
CAS Number
– 1073560-68-5
Molecular Weight
– C47H52N4O7
SMILES
– C(OC(N([C@H](C(N[C@H](C(=O)N1[C@H](C(N[C@@H]([C@H](C2=CC=CC=C2)C3=CC=CC=C3)C(O)=O)=O)CCC1)C4CCCCC4)=O)C)C)=O)C5C=6C(C=7C5=CC=CC7)=CC=CC6
Target
– Others
Pathway
– Others
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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