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(E/Z)-TG003
Products Details
Product Description
– (E/Z)-TG003 is a racemic compound of (Z)-TG003 and (E)-TG003. (Z)-TG003 is a potent inhibitor of Clk1/Sty; inhibits Clk1 and Clk4 with IC50 values of 20 and 15 nM, respectively[1].
Web ID
– HY-15338A
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C13H15NO2S
References
– [1]Muraki M, et al. Manipulation of alternative splicing by a newly developed inhibitor of Clks. J Biol Chem. 2004 Jun 4;279(23):24246-54.
CAS Number
– 300801-52-9
Molecular Weight
– 249.33
SMILES
– COC(C=C1N/2CC)=CC=C1SC2=CC(C)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
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