(E/Z)-BCI
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(E/Z)-BCI

SKU T11139-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 117 CAD through 1,888 CAD

Products Details

Product Description

– (E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROS production in macrophage cells by activating the Nrf2 signaling axis and inhibiting the NF-κB pathway.

Web ID

– T11139

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H23NO

References

– Zhang F, et al. DUSP6 Inhibitor (E/Z)-BCI Hydrochloride Attenuates Lipopolysaccharide-Induced Inflammatory Responses in Murine Macrophage Cells via Activating the Nrf2 Signaling Axis and Inhibiting the NF-κB Pathway. Inflammation. 2019 Apr;42(2):672-681.

CAS Number

– 15982-84-0

Molecular Weight

– C22H23NO

Compound Purity

– 0.9994

SMILES

– O=C1C(=Cc2ccccc2)C(NC2CCCCC2)c2ccccc12

Target

– Endogenous Metabolite|||Vitamin

Pathway

– Apoptosis|||Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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