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Products Details
Product Description
– The Ki value of DOT1L-in-1 is 2pm.It is a highly effective, selective and novel Dot1L inhibitor.
Web ID
– T11081
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C32H36ClN9O2S
References
– Möbitz H, et al. Discovery of Potent, Selective, and Structurally Novel Dot1L Inhibitors by a Fragment Linking Approach. ACS Med Chem Lett. 2017 Feb 14;8(3):338-343.
CAS Number
– 2088518-50-5
Molecular Weight
– C32H36ClN9O2S
SMILES
– ClC1=C(C=2C(S1)=CC=C(NC(NCC(NCCCN(C)[C@H]3CN(CCC3)C4=C5C(=NC=N4)NC=C5)=O)=O)C2)C6=C(C)N=CC=C6
Target
– PDE
Pathway
– Chromatin/Epigenetic
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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