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DI-404
Price range: 4,496 CAD through 8,112 CAD
Products Details
Product Description
– DI-404 is a high-Affinity Peptidomimetic the DCN1-UBC12 Protein-Protein Interaction inhibitor (Kd= 6.9 nM). DI-404 effectively and selectively inhibits the neddylation of cullin 3 over other cullin members.
Web ID
– T23989
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C35H45ClN6O6S
References
– ZHou HB, Zhou W, Zhou B, Liu L, Chern TR, Chinnaswamy K, Lu J, Bernard D, Yang C, Li S, Wang M, Stuckey JA, Sun Y, Wang S. High-Affinity Peptidomimetic Inhibitors of the DCN1-UBC12 Protein-Protein Interaction. J Med Chem. 2018 Feb 13. doi: 10.1021/acs.jmedchem.7b01455. [Epub ahead of print] PubMed PMID: 29438612.
CAS Number
– 2187412-79-7
Molecular Weight
– C35H45ClN6O6S
SMILES
– C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H]1C=2C(OCC1)=CC=CC2)=O)CCCCN)=O)[C@H]3CCOCC3)=O)NC(CC)=O)C=4SC=5C(N4)=CC=C(Cl)C5
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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