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DC44SMe
2,432 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– The IC50 of DC44SMe for Ramos, Namalwa and HL60 / s cancer cells was 2.0 nM, 2.8 nM and 1.9 nM, respectively. DC44SMe can be used for targeted treatment of cancer. DC44SMe is a phosphate prodrug of DC44 and can be used in the synthesis of antibody-drug conjugates (ADC).
Web ID
– T10975
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C38H37ClN5O7PS2
References
– Zhao RY, et al. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer. J Med Chem. 2012 Jan 26;55(2):766-82.
CAS Number
– 1354787-76-0
Molecular Weight
– C38H37ClN5O7PS2
SMILES
– C(=O)(N1C2=C(C=3C(C(OP(=O)(O)O)=C2)=CC=CC3)[C@H](CCl)C1)C=4NC=5C(C4)=CC(NC(=O)C=6NC=7C(C6)=CC(NC(CCC(SSC)(C)C)=O)=CC7)=CC5
Target
– ADC Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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