DC-LC3in-D5
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DC-LC3in-D5

SKU T61871-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 168 CAD through 4,144 CAD

Products Details

Product Description

– DC-LC3in-D5 is a potent and selective covalent inhibitor of LC3A/B that disrupts autophagy by covalently binding to Lys49 on LC3B (IC₅₀ = 200 nM), resulting in impaired LC3B lipidation, accumulation of the autophagy substrate p62, and a significant reduction in the formation of autophagosome vesicles.

Web ID

– T61871

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H22Cl2N2O3

CAS Number

– 2868312-73-4

Molecular Weight

– C19H22Cl2N2O3

Compound Purity

– 0.9979

SMILES

– O=C1C(=CNCCN2CCOCC2)C(=O)CC(C=3C=CC=C(Cl)C3Cl)C1

Pathway

– Autophagy

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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