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CY-09
Price range: 88 CAD through 2,128 CAD
Products Details
Product Description
– CY-09 is an NLRP3 inhibitor.
Web ID
– T4164
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H12F3NO3S2
Citations
– 1. Jia Y, Cui R, Wang C, et al. Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway. Redox Biology. 2020: 101534.
2. Jia Y, Cui R, Wang C, et al. Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway. Redox Biology. 2020: 101534.
3. Zhang Y, Liu Y, Xie Z, et al.Inhibition of PFKFB Preserves Intestinal Barrier Function in Sepsis by Inhibiting NLRP3/GSDMD.Oxidative Medicine and Cellular Longevity.2022, 2022.
4. Zhu Q, Zheng F, You W, et al.Expression of histone H1 in rats with traumatic brain injury and the effect of the NLRP3 inflammasome pathway.World Neurosurgery.2022
References
– Jiang H, et al. Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders. J Exp Med. 2017 Nov 6;214(11):3219-3238.
CAS Number
– 1073612-91-5
Molecular Weight
– C19H12F3NO3S2
Compound Purity
– 0.9925
SMILES
– OC(=O)c1ccc(C=C2SC(=S)N(Cc3cccc(c3)C(F)(F)F)C2=O)cc1
Pathway
– NF-κB|||Immunology/Inflammation
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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