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Products Details
Product Description
– CSF1R-IN-4 is a potent inhibitor of CSF1R. CSF-1R is expressed in macrophages, and the survival and differentiation of macrophages depends on the CSF-1/CSF-1R signaling pathway. CSF1R-IN-4 affects the exchange of inflammatory factors between TAMs and glioma cells. CSF1R-IN-4 has the potential for the research of cancer disease (extracted from patent WO2021197276A1, compound 104)[1].
Web ID
– HY-144040
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H20N6O3
References
– [1]Wei-Guo Su, et al. Amide compounds and uses thereof. Patent WO2021197276A1.
CAS Number
– 2716185-86-1
Molecular Weight
– 428.44
SMILES
– O=C(C1=CC=CN(C2CC2)C1=O)NC3=NC=C(OC4=CC(C5=CN(C)N=C5)=NC=C4)C=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– c-Fms
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
