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Products Details
Product Description
– CRT 0105446 (compound 22d) is a LIMK1 inhibitor, with an IC50 of 8 nM[1].
Web ID
– HY-123345
Shipping
– Room temperature
Molecular Formula
– C20H18F3N3O2S
References
– [1]Mark D Charles, et al. Discovery, Development, and SAR of Aminothiazoles as LIMK Inhibitors with Cellular Anti-Invasive Properties. J Med Chem. 2015 Oct 22;58(20):8309-13.
CAS Number
– 1661846-05-4
Molecular Weight
– 421.44
SMILES
– CC(C(NC1=NC=C(S1)C2=C(C=NC=C2)C3=CC=C(C=C3C(F)(F)F)OC)=O)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– LIM Kinase (LIMK)
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
