CP-673451
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CP-673451

SKU T6091-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 70 CAD through 2,704 CAD

Products Details

Product Description

– CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than other angiogenic receptors.

Web ID

– T6091

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H27N5O2

Citations

– 1. Yang Y L, Cao L B, He W R, et al. Endocytosis triggers V-ATPase-SYK–mediated priming of cGAS activation and innate immune response. Proceedings of the National Academy of Sciences. 2022, 119(43): e2207280119. 2. Yang L, Wang X, Zhou X, et al.A tunable human intestinal organoid system achieves controlled balance between self-renewal and differentiation.Nature Communications.2025, 16(1): 315.

References

– Roberts WG, et al. Cancer Res, 2005, 65(3), 957-966.

CAS Number

– 343787-29-1

Molecular Weight

– C24H27N5O2

Compound Purity

– 0.9993

SMILES

– COCCOc1ccc2n(cnc2c1)-c1ccc2cccc(N3CCC(N)CC3)c2n1

Pathway

– Angiogenesis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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