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Coralyne chloride
Price range: 51 CAD through 1,075 CAD
Products Details
Product Description
– Coralyne chloride is a protoberberine with strong anticancer activity. It can be used to prepare Coralyne derivatives, a fluorescent DNA-based molecular rectifier built into DNA duplexes through site-specific insertion. It acts as a topoisomerase I toxic molecule, inducing topoisomerase I-mediated DNA cleavage.
Web ID
– T31011
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H22ClNO4
Citations
– 1. Zu S, Long Z, Zhang X, et al.A Comparative Study on the DNA Interactions and Biological Activities of Benzophenanthridine and Protoberberine Alkaloids.Journal of Natural Products.2024
References
– Khadka DB, Cho WJ. Topoisomerase inhibitors as anticancer agents: a patent update. Expert Opin Ther Pat. 2013 Aug;23(8):1033-56.
CAS Number
– 38989-38-7
Molecular Weight
– C22H22ClNO4
Compound Purity
– 0.9935
SMILES
– [Cl-].COc1cc2cc[n+]3c(C)c4cc(OC)c(OC)cc4cc3c2cc1OC
Pathway
– DNA Damage/DNA Repair
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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