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Col003
Price range: 62 CAD through 1,968 CAD
Products Details
Product Description
– Col003 is a selective and potent inhibitor of Hsp47, competitively binding to the collagen-binding site on Hsp47 (IC50: 1.8 μM). It is useful for researching fibrosis.
Web ID
– T10860
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C14H11NO4
Citations
– 1. Wang J, Bai M, Zhang C, et al.Natural compound fraxinellone ameliorates intestinal fibrosis in mice via direct intervention of HSP47-collagen interaction in the epithelium.Acta Pharmacologica Sinica.2023: 1-10.
References
– Ito S, et al. A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis. J Biol Chem. 2017 Dec 8;292(49):20076-20085.
CAS Number
– 328565-16-8
Molecular Weight
– C14H11NO4
Compound Purity
– 0.9903
SMILES
– Oc1c(C=O)cc(Cc2ccccc2)cc1[N+]([O-])=O
Target
– Others
Pathway
– Cytoskeletal Signaling|||Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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