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Products Details
Product Description
– Clofarabine-5′-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5′-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.
Web ID
– T203181
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C10H13ClFN5O9P2
CAS Number
– 167620-89-5
Molecular Weight
– C10H13ClFN5O9P2
SMILES
– F[C@@H]1[C@H](N2C=3C(N=C2)=C(N)N=C(Cl)N3)O[C@H](COP(OP(=O)(O)O)(=O)O)[C@H]1O
Target
– EGFR
Pathway
– Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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