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Cilengitide
Price range: 72 CAD through 1,066 CAD
Products Details
Product Description
– Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays) with approximately 10-fold selectivity against gpIIbIIIa.
Web ID
– T2494
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H40N8O7
Citations
– 1. Xing Q, Feng Y, Sun H, et al. Scavenger receptor MARCO contributes to macrophage phagocytosis and clearance of tumor cells. Experimental Cell Research. 2021: 112862
References
– Hariharan S, et al. Assessment of the biological and pharmacological effects of the alpha nu beta3 and alpha nu beta5 integrinreceptor antagonist, Cilengitide (EMD 121974), in patients with advanced solid tumors. Ann Oncol. 2007 Aug;18(8):1400-7.
CAS Number
– 188968-51-6
Molecular Weight
– C27H40N8O7
Compound Purity
– 0.998
SMILES
– CC(C)[C@@H]1N(C)C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O
Pathway
– Cytoskeletal Signaling|||Autophagy
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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