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Chlorisondamine (diiodide)
$280
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Products Details
Product Description
– Chlorisondamine (diiodide) is a potent nicotinic acetylcholine receptor (nAChR) antagonist and a ganglion blocker. Chlorisondamine antagonizes some of nicotine’s central actions in a potent, long-lasting and pharmacologically selective way[1].
Web ID
– HY-101347
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C14H20Cl4I2N2
References
– [1]Clarke PB, et al. The pharmacology of the nicotinic antagonist, chlorisondamine, investigated in rat brain and autonomic ganglion. Br J Pharmacol. 1994 Feb;111(2):397-405. |[2]Clarke PB. Chronic central nicotinic blockade after a single administration of the bisquaternary ganglion-blocking drug chlorisondamine. Br J Pharmacol. 1984;83(2):527-535. doi:10.1111/j.1476-5381.1984.tb16517.x|[3]Clarke PB. Chronic central nicotinic blockade after a single administration of the bisquaternary ganglion-blocking drug chlorisondamine. Br J Pharmacol. 1984;83(2):527-535. doi:10.1111/j.1476-5381.1984.tb16517.x
CAS Number
– 96750-66-2
Molecular Weight
– 611.94
Compound Purity
– 98.0
SMILES
– C[N+](CC[N+]1(C)CC2=C(C(Cl)=C(Cl)C(Cl)=C2Cl)C1)(C)C.[I-].[I-]
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– nAChR
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
