Download Files:
Products Details
Product Description
– CHK-336 (Example 1) is an orally active LDHA inhibitor (IC50<1 nM) that inhibits lactate production in mouse hepatocytes. CHK-336 can be used in the study of hyperoxaluria[1].
Web ID
– HY-156683
Shipping
– Room temperature
Molecular Formula
– C24H20F2N4O4S2
References
– [1]David Andrew Powell, et al. Substituted pyrazolyl compounds and methods of use thereof. Patent WO2021234547A1.
CAS Number
– 2743436-86-2
Molecular Weight
– 530.57
SMILES
– O=C(C1=CSC(N2N=C(C(CC3=CC=C(S(=O)(N)=O)C(F)=C3)=C2CC4CC4)C5=CC=C(F)C=C5)=N1)O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Lactate Dehydrogenase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
