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Products Details
Product Description
– Chitin synthase inhibitor 14 (compound 4n) is chitin synthase (CHS) inhibitor. Chitin synthase inhibitor 14 has antifungal activity while possessed the potency against drug-resistant fungal variants[1].
Web ID
– HY-149585
Shipping
– Room temperature
Molecular Formula
– C25H26ClN5O5
References
– [1]Liu L, et al. Novel spiro[pyrrolidine-2,3′-quinoline]-2′-one derivatives containing piperazine fragment as potential chitin synthase inhibitors and antifungal agents: Design, synthesis and biological evaluation. Eur J Med Chem. 2023 Nov 15;260:115777.
CAS Number
– 2922114-19-8
Molecular Weight
– 511.96
SMILES
– O=C1C2(CCCN2C(CN3CCN(C(C4=C(Cl)C=CC([N+]([O-])=O)=C4)=O)CC3)=O)CC5=CC=CC=C5N1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Fungal
Pathway
– Anti-infection
Product type
– Reference compound
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