CHIR-124

SKU T6350-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 56 CAD through 603 CAD

Products Details

Product Description

– CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.

Web ID

– T6350

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H22ClN5O

References

– Tse AN, et al, Clin Cancer Res, 2007, 13(2 Pt 1), 591-602.

CAS Number

– 405168-58-3

Molecular Weight

– C23H22ClN5O

Compound Purity

– 0.97

SMILES

– Clc1ccc2[nH]c(=O)c(-c3nc4ccccc4[nH]3)c(N[C@@H]3CN4CCC3CC4)c2c1

Pathway

– Stem Cells|||Apoptosis|||PI3K/Akt/mTOR signaling|||Angiogenesis|||Cell Cycle/Checkpoint|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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