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Cetirizine methyl ester

Products Details

Product Description

– Cetirizine methyl ester is an impurity of Cetirizine (HY-17042). Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist[1].

Web ID

– HY-12966

Shipping

– Room temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C22H27ClN2O3

References

– [1]Do JA, et al. Collision-induced dissociation pathways of H1-antihistamines by electrospray ionization quadrupole time-of-flight mass spectrometry. Arch Pharm Res. 2017 Jun;40(6):736-745.

CAS Number

– 83881-46-3

Molecular Weight

– 402.91

SMILES

– O=C(COCCN1CCN(C(C2=CC=C(C=C2)Cl)C3=CC=CC=C3)CC1)OC

Clinical Information

– Launched

Research Area

– Endocrinology; Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Histamine Receptor

Pathway

– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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