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CDKI-73
Price range: 234 CAD through 2,224 CAD
Products Details
Product Description
– CDKI-73 is a potent CDK9 inhibitor (Ki: 4 nM). It shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM).The inhibition of CDK9 induces apoptosis and potentiates the effect of cisplatin.
Web ID
– T14919
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H15FN6O2S2
References
– Xie S, et al. Antitumor action of CDK inhibitor LS-007 as a single agent and in combination with ABT-199 against human acute leukemia cells. Acta Pharmacol Sin. 2016 Nov;37(11):1481-1489.
CAS Number
– 1421693-22-2
Molecular Weight
– C15H15FN6O2S2
Compound Purity
– 0.9811
SMILES
– CNc1nc(C)c(s1)-c1nc(Nc2cccc(c2)S(N)(=O)=O)ncc1F
Target
– Others
Pathway
– Apoptosis|||Cell Cycle/Checkpoint
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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